| Human Cadaver Skin was used. All samples were from the same subject, a 60 year old male with no skin diseases. The commercial formulation consisted of 20% MPA, 75% Xylene, 5% Dispersing agents. 0.5534g of this formulation was watered down in 100ml of water.The loading was given as 64.26nmol/cm2 and the concentration was given as 4.2micromol/ml. I converted these figures from mols to grams and used them together with the volume added to calculate the area of skin exposed. The figure calculated for this does not agree with that calculated for the previous study however. They did give kp as 0.00142, but this does not seem to agree with the concentration that they gave so I have left this off the database. |
