The skin samples came from the cadaver of a 39 year old caucsian male. The skin was still viable. % Penetrated was calculated by adding together the amount found in the receptor fluid and the amount that had entered the skin including the stratum corneum. In the paper they did this slightly differently, they included the amount that was found solubilised in the skin as absorbed (3.9%) but did not include the amount that remained in the solid precipitate after the skin was homogenized (6.1%) Concentration was given as 12 picomoles/microlitre. I converted this to mg/ml for the database. |