| Sprague-Dawley Rats were used. For More Experimental Detail See Bronaugh RL, (1991) A flow-through diffusion cell. In In Vitro Percutaneous Absorption: Principles, Fundamentals, and Applications. Edited by R.L Bronaugh and HI Maibach. Pp. 223-230 CRC Press. % Penetrated was calculated from adding together the amount found in the receptor fluid to the amount found in the skin digest at the end of the experiment. The skin was washed with an aqueous radiac soap solution at 24 hours and immediately after that there was an increase in absorption |
