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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
MbOCA812EthanolRatDorsalFull Thickness Skin0.32Flow-through7272 67.31.3  126104
MbOCA813EthanolRatDorsalFull Thickness Skin0.32Flow-through7272 63.51.8  156104
MbOCA814EthanolHumanBreastFull Thickness Skin0.32Flow-through7272 33.72.4  1010104
MbOCA815EthanolHumanDorsalFull Thickness Skin0.32Flow-through7272 48.15.9  1510104
MDA816EthanolRatDorsalFull Thickness Skin0.32Flow-through7272 63.76.1  122104
MDA817EthanolRatDorsalFull Thickness Skin0.32Flow-through7272 66.413.3  162104
MDA818EthanolHumanBreastFull Thickness Skin0.32Flow-through7272 36.813  102104
MDA819EthanolHumanBreastFull Thickness Skin0.32Flow-through7272 70.332.9  142104
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