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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Hippuric Acid821AcetoneHumanAbdomenFull Thickness Skin1Static4848  1.2  15 105
Nicotinic Acid822AcetoneHumanAbdomenFull Thickness Skin1Static4848  3.3  19 105
Thiourea823AcetoneHumanAbdomenFull Thickness Skin1Static4848  3.4  52 105
Chloramphenicol824AcetoneHumanAbdomenFull Thickness Skin1Static4848  2.9  12 105
Phenol825AcetoneHumanAbdomenFull Thickness Skin1Static4848  10.9  7 105
Urea826AcetoneHumanAbdomenFull Thickness Skin1Static4848  11.1  22 105
Nicotinamide827AcetoneHumanAbdomenFull Thickness Skin1Static4848  28.8  21 105
Acetylcysteine828AcetoneHumanAbdomenFull Thickness Skin1Static4848  40.5  14 105
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