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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Ibuprofen1134pH 3 phosphate bufferSnakeNot GivenFull Thickness Skin Static66    0.0881  170
Methyl-4-hydroxybenzoate1135pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static66    0.00267  170
Ethyl 4-hydroxybenzoate1136pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static66    0.00497  170
Propyl 4-hydroxybenzoate1137pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static66    0.00875  170
Butyl 4-hydroxybenzoate1138pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static66    0.0226  170
Hydrocortisone1139pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static      2.28E-05  170
Corticosterone1140pH 7.2 phosphate bufferSnakeNot GivenFull Thickness Skin Static7272    0.000127  170
Ketoprofen1141pH 3 phosphate bufferSnakeNot GivenFull Thickness Skin Static2424    0.00622  170
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