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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
1-Methoxypropan-2-ol1431WaterHumanBreastDermatomed to 0.5mm0.64Flow-through242494.12.292.294.33 5 221
2-Ethoxyethanol1432WaterHumanBreastDermatomed to 0.5mm0.64Flow-through2424102.45.25.0912.89 4 221
2-Butoxyethanol1433WaterHumanBreastDermatomed to 0.5mm0.64Flow-through242488.4527.6527.3964.29 5 221
2-Ethoxyethanol1434WaterHumanBreastDermatomed to 0.5mm0.64Flow-through242496.2914.414.12  5 221
2-Butoxyethanol1435WaterHumanBreastDermatomed to 0.5mm0.64Flow-through2424106.2115.915.7630.84 8 221
2-Ethoxyethanol1436WaterHumanBreastDermatomed to 0.5mm0.64Flow-through2424109.3418.2717.897.69 6 221
2-Butoxyethanol1437WaterHumanBreastDermatomed to 0.5mm0.64Flow-through2424108.3623.2123.05105.65 6 221
2-Ethoxyethanol1438WaterHumanBreastDermatomed to 0.5mm0.64Flow-through242487.1711.411.2625.32 4 221
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