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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Urea1580EthanolMouseAbdomenFull Thickness Skin4.9Static66    0.000124 251
Glucose1581EthanolMouseAbdomenFull Thickness Skin4.9Static66    9.5E-054 251
Glycerol1582EthanolMouseAbdomenFull Thickness Skin4.9Static66    0.000144 251
Thiourea1583EthanolMouseAbdomenFull Thickness Skin4.9Static66    9.6E-054 251
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