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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Caffeine18AcetoneHumanAbdomenFull Thickness Skin3.14Static2424  32.6  6 3
Caffeine19AcetoneHumanAbdomenFull Thickness Skin3.14Static2424  3.9  8 3
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