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Chemical Study No. VehicleSpeciesSiteDose (ml)Area (cm2)Concentration mg/mlExposure Time (h)Length of Study (h)% AbsorbedMaximal Flux (mcrg/cm2/h)nkp (cm/h)Lag Time (h)Reference Number
Beta-Estradiol154EthanolHuman skin grafted ratAbdomen60.831.14   30.0019 35
Beta-Estradiol155PBSHuman skin grafted ratAbdomen60.80.00031344   30.065 35
Beta-Estradiol156Ethanol (75%)Human skin grafted ratAbdomen60.80.000314   30.002 35
Beta-Estradiol157Ethanol (95%)Human skin grafted ratAbdomen60.80.00031344   30.0051 35
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