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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Benzoic Acid1199PetrolatumRatBackFull Thickness Skin1.13Static      0.0003106182
Benzoic Acid1200PetrolatumRatBackFull Thickness Skin1.13Static55  0.5  10 182
Benzoic Acid1201PetrolatumRatAbdomenFull Thickness Skin1.13Static      0.00029131182
Benzoic Acid1202PetrolatumRatAbdomenFull Thickness Skin1.13Static55  5.1  13 182
Benzoic Acid1203PetrolatumRatBackFull Thickness Skin1.13Static      0.0004573.5182
Benzoic Acid1204PetrolatumRatBackFull Thickness Skin1.13Static55  2.5  7 182
Benzoic Acid1205PetrolatumRatAbdomenFull Thickness Skin1.13Static      0.00044131.2182
Benzoic Acid1206PetrolatumRatAbdomenFull Thickness Skin1.13Static55  6.5  13 182
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