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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Benzoic Acid162EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 49.547.3  12 30
Benzoic Acid163EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 60.159.1  12 30
4-Aminobenzoic acid164EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 25.75  12 30
4-Aminobenzoic acid165EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 33.418.7  12 30
Benzocaine166EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 76.675.1  12 30
Benzocaine167EthanolGuinea pigNot GivenDermatomed to 0.2mm0.64Flow-through2448 77.876  12 30
Benzocaine168EthanolHumanAbdomenDermatomed to 0.2mm0.64Flow-through2448 49.548  4 30
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