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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Progesterone173WaterHumanNot GivenIsolated Epidermis Static     0.000943350.0015  36
Pregnenolone175WaterHumanNot GivenIsolated Epidermis Static     0.0016230.0015  36
Testosterone176WaterHumanNot GivenIsolated Epidermis Static     0.001150.0004 236
Aldosterone177WaterHumanNot GivenIsolated Epidermis Static     7.93E-073E-06  36
Hydrocortisone178WaterHumanNot GivenIsolated Epidermis Static     2E-063E-06  36
Corticosterone179WaterHumanNot GivenIsolated Epidermis Static     3.6E-056E-05  36
Cortisone180WaterHumanNot GivenIsolated Epidermis Static     3.5E-061E-05 22036
Cortexolone181WaterHumanNot GivenIsolated Epidermis Static     0.0002597.5E-05  36
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