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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Ethanol4590.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static0.50.5    0.00218 65
Ethanol4600.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static5.55.5    0.00228 65
Ethanol4610.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static10.510.5    0.00238 65
Ethanol4620.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static15.515.5    0.00228 65
Ethanol4630.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static20.520.5    0.00218 65
Ethanol4640.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static25.525.5    0.0028 65
Ethanol4650.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static29.529.5    0.00198 65
Water4660.9% SalineMouseAbdomen/DorsalFull Thickness Skin0.6Static0.50.5    0.00168 65
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