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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Testosterone63EthanolHumanAbdomenFull Thickness Skin0.64Static2222  9.7 0.000125 15
Testosterone64EthanolRatAbdomenIsolated Epidermis0.64Static2222  11.8 0.00025 15
Testosterone65EthanolHumanAbdomenFull Thickness Skin0.64Static2222  34.8 0.000535 15
Testosterone66EthanolRatAbdomenIsolated Epidermis0.64Static2222  58 0.002875 15
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