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IN VITRO DATA
Page 1 of 2.
10
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Membrane
Area (cm2)
Cell Type
Exposure Time (h)
Length of Study(h)
% Recovery
% Penetrated
% Absorbed
s-s-flux (mcrg/cm2/h)
kp (cm/h)
n
Lag Time (h)
Ref.No
Pyrene
1072
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
86
69.9
57.4
5
153
Pyrene
1073
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
78.3
67.9
52.8
5
153
Pyrene
1074
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
62
40.8
26.9
5
153
Benzo[a]pyrene
1075
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
87.9
67.4
37
5
153
Benzo[a]pyrene
1076
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
83.6
48.9
10.2
5
153
Benzo[a]pyrene
1077
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
75.5
39.8
7.2
5
153
DEHP
1078
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
84.7
47
6.1
5
153
DEHP
1079
Acetone
Guinea pig
Back
Dermatomed to 0.2mm
0.64
Flow-through
24
24
86.5
45.2
5
5
153
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IN VIVO DATA
Page 1 of 1
3
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Dose (ml)
Area (cm2)
Concentration mg/ml
Exposure Time (h)
Length of Study (h)
% Absorbed
Maximal Flux (mcrg/cm2/h)
n
kp (cm/h)
Lag Time (h)
Reference Number
Pyrene
565
Acetone
Guinea pig
Dorsal
0.05
4
2
24
168
93.9
5
153
Benzo[a]pyrene
566
Acetone
Guinea pig
Dorsal
0.05
4
2.24
24
168
73.3
5
153
DEHP
567
Acetone
Guinea pig
Dorsal
0.05
4
4.24
24
168
53.1
5
153
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