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IN VITRO DATA
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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Benzo[a]pyrene1625AcetoneMousedorsalFull Thickness Skin2Flow-through161696.91 6.75  5 281
Benzo[a]pyrene1626AcetoneMousedorsalFull Thickness Skin2Flow-through1616100.84 6.84  10 281
Benzo[a]pyrene1627AcetoneMousedorsalFull Thickness Skin2Flow-through161692.11 9.35  10 281
Benzo[a]pyrene1628AcetoneMousedorsalFull Thickness Skin2Flow-through161694.03 9.17  10 281
Benzo[a]pyrene1629AcetoneMousedorsalFull Thickness Skin2Flow-through161697.47 4.39  10 281
Benzo[a]pyrene1630AcetoneHairless MousedorsalFull Thickness Skin2Flow-through161690.01 2.89  10 281
Benzo[a]pyrene1631AcetoneHairless MousedorsalFull Thickness Skin2Flow-through161690.77 1.98  9 281
Testosterone1632AcetoneMousedorsalFull Thickness Skin2Flow-through161694.15 76.59  5 281
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