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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Testosterone12995% aq. EthanolHumanBreast/AbdomenDermatomed to 0.6mm0.2Static88 6.911.33  6 32
Testosterone13295% aq. EthanolHumanBreast/Abdomen Scar TissueDermatomed to 0.6mm0.2Static88 5.820.56  6 32
Progesterone13395% aq. EthanolHumanBreast/AbdomenDermatomed to 0.6mm0.2Static88 9.030.71  4 32
Progesterone13495% aq. EthanolHumanBreast/Abdomen Scar TissueDermatomed to 0.6mm0.2Static88 4.540.23  4 32
Beta-Estradiol13595% aq. EthanolHumanBreast/AbdomenDermatomed to 0.6mm0.2Static2424 36.940.027  5 32
Beta-Estradiol13695% aq. EthanolHumanBreast/Abdomen Scar TissueDermatomed to 0.6mm0.2Static2424 35.170.0016  5 32
Hydrocortisone13795% aq. EthanolHumanBreast/AbdomenDermatomed to 0.6mm0.2Static2424 52.110.03  4 32
Hydrocortisone13895% aq. EthanolHumanBreast/Abdomen Scar tissueDermatomed to 0.6mm0.2Static2424 45.60.014  4 32
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