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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Dipropylene glycol methyl ether1725undilutedHumanabdomenFull Thickness Skin3.29Static88  0.32106.30.000111.5E-051.51346
Dipropylene glycol methyl ether172650% in waterHumanabdomenFull Thickness Skin3.29Static88  0.2742.48E-051.5E-052.17346
n-Propoxyethanol1728undilutedHumanabdomenFull Thickness Skin3.29Static88  1.553940.000438E-051.15346
n-Propoxyethanol172950% in waterHumanabdomenFull Thickness Skin3.29Static88  3.35650.001030.000171.9346
2-Isopropoxyethanol1730undilutedHumanabdomenFull Thickness Skin3.29Static88  0.912400.000276.8E-051.32346
2-Isopropoxyethanol173150% in waterHumanabdomenFull Thickness Skin3.29Static88  1.552460.000443.8E-051.97346
2-Methoxyethyl acetate1734undillutedHumanAbdomenFull Thickness Skin3.29Static88  3.268310.000830.000111.07346
2-Methoxyethyl acetate173550% in waterHumanabdomenFull Thickness Skin3.29Static88  5.379020.001810.000251.54346
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