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Chemical Name:			Species:
Vehicle:			Cell Type:

Average (Mean) Results for Coumarin with All Species Skin

Lag Time	Kp	Flux
0.58	0.0108	0.17175

Page 1 of 2. 9 In Vitro Records Found for Coumarin with All Species Skin, All Cells

Click the Study No. for further experimental detail

Chemical	Study No.	Vehicle	Species	Site	Membrane	Area (cm2)	Cell Type	Exposure Time (h)	Study Length (h)	% Recovery	% Absorbed	s-s-flux (mcrg/cm2/h)	kp (cm/h)	n	Lag Time (h)	Ref.No
Coumarin	670	Ethanol	Human	Breast	Full Thickness Skin	0.32	Flow-through	72	72	74.6	50.4	0.0752		9	1.1	77
Coumarin	671	Ethanol	Rat	Dorsal	Full Thickness Skin	0.32	Flow-through	72	72	77.7	51.3	0.157		12	0.2	77
Coumarin	672	Ethanol	Mouse	Dorsal	Full Thickness Skin	0.32	Flow-through	72	72	83.9	44.9	0.1996		18	0.2	77
Coumarin	673	Ethanol	Human	Breast	Full Thickness Skin	0.32	Flow-through	72	72	85.2	66	0.1438		9	0.8	77
Coumarin	674	Ethanol	Rat	Dorsal	Full Thickness Skin	0.32	Flow-through	72	72	79.7	60.4	0.1517		12	0.2	77
Coumarin	675	Ethanol	Mouse	Dorsal	Full Thickness Skin	0.32	Flow-through	72	72	90.5	75	0.3447		18	0.2	77
Coumarin	676	Ethanol	Mouse	Dorsal	Full Thickness Skin	0.32	Flow-through	72	72		64.1			18		77
Coumarin	1509	Phosphate Buffer (pH 7.4)	Human	Abdomen	Full Thickness Skin	0.636	Static	48	48			0.13	0.0091	5	1.61	236
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