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IN VITRO DATA

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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
2-Nitro-1,4-Benzenediamine683EthanolHumanAbdomenNot Given0.64Flow-through0.52472.69.25.3  8 81
2-Nitro-1,4-Benzenediamine684Semi-Permenant Hair Dye FormulationHumanAbdomenNot Given0.64Flow-through0.52463.89.57.1  8 81
2-Nitro-1,4-Benzenediamine685EthanolRatNot GivenNot Given0.64Flow-through0.52468.49.34.3  12 81
2-Nitro-1,4-Benzenediamine686Semipermenant Hair Dye FormulationRatNot GivenNot Given0.64Flow-through0.52478.86.93.8  12 81
2-Nitro-1,4-Benzenediamine68750% aq. Permenant Oxidative Hair Dye + H2O2RatNot GivenNot Given0.64Flow-through0.524744.21.53  12 81
2-Nitro-1,4-Benzenediamine688Control Diluted Permenant hair dye (no H2O2)RatNot GivenNot Given0.64Flow-through0.52471.65.33.1  12 81
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