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Chemical Study No. Vehicle SpeciesSite Membrane Area (cm2)Cell TypeExposure Time (h)Length of Study(h)% Recovery% Penetrated% Absorbeds-s-flux (mcrg/cm2/h)kp (cm/h)nLag Time (h)Ref.No
Salicylic acid1424dimethyl isosorbide & 2-propanolRatNot GivenFull Thickness Skin3.14Static4848  95.819.75 33.5220
Butyl salicylate1425dimethyl isosorbide & 2-propanolRatNot GivenFull Thickness Skin3.14Static4848  6416.7 61.7220
Salicylamide1426dimethyl isosorbide & 2-propanolRatNot GivenFull Thickness Skin3.14Static4848  7914.4 32220
Diethylamine salicylate1427dimethyl isosorbide & 2-propanolRatNot GivenFull Thickness Skin3.14Static4848  7910.77 65220
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Page 1 of 1 4 records found
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Chemical Study No. VehicleSpeciesSiteDose (ml)Area (cm2)Concentration mg/mlExposure Time (h)Length of Study (h)% AbsorbedMaximal Flux (mcrg/cm2/h)nkp (cm/h)Lag Time (h)Reference Number
Salicylic acid805dimethylisosorbide + 2-propanolRatFlankNot Given5.08 242477 5  220
Butyl salicylate806dimethylisosorbide + 2-propanolRatFlankNot Given5.08 242499.77 5  220
Salicylamide807dimethylisosorbide + 2-propanolRatFlankNot Given5.08 242471.2 5  220
Diethylamine salicylate808dimethylisosorbide + 2-propanolRatFlankNot Given5.08 242431 5  220
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