DATA BY REFERENCE
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IN VITRO DATA
Page 1 of 1.
5
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Membrane
Area (cm2)
Cell Type
Exposure Time (h)
Length of Study(h)
% Recovery
% Penetrated
% Absorbed
s-s-flux (mcrg/cm2/h)
kp (cm/h)
n
Lag Time (h)
Ref.No
Salicylic acid
634
Ethanol
Pig
Not Given
Full Thickness Skin
10
None
8
8
75.4
24.13
0.43
5
74
Theophylline
635
Ethanol
Pig
Not Given
Full Thickness Skin
10
None
8
8
80
34.8
0.6
5
74
4-Aminobenzoic acid
636
Ethanol
Pig
Not Given
Full Thickness Skin
10
None
8
8
76.9
18.23
0.73
5
74
DEHP
637
Ethanol
Pig
Not Given
Full Thickness Skin
10
None
8
8
94.1
18.34
0.14
5
74
2,4 Dimethylamine
638
Ethanol
Pig
Not Given
Full Thickness Skin
10
None
8
8
31.2
8.6
1.5
5
74
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IN VIVO DATA
Page 1 of 1
5
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Dose (ml)
Area (cm2)
Concentration mg/ml
Exposure Time (h)
Length of Study (h)
% Absorbed
Maximal Flux (mcrg/cm2/h)
n
kp (cm/h)
Lag Time (h)
Reference Number
Salicylic acid
249
Ethanol
Human
Ventral Forearm
0.05
10
0.48
24
168
6.5
6
74
Theophylline
250
Ethanol
Human
Ventral Forearm
0.05
10
0.65
24
168
16.9
6
74
4-Aminobenzoic acid
251
Ethanol
Human
Ventral Forearm
0.05
10
4.3
24
168
15.3
5
74
DEHP
252
Ethanol
Human
Ventral Forearm
0.05
10
3.7
24
168
1.8
6
74
2,4 Dimethylamine
253
Ethanol
Human
Ventral Forearm
0.05
10
7.94
24
168
1.1
6
74
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