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IN VITRO DATA
Page 1 of 1.
5
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Membrane
Area (cm2)
Cell Type
Exposure Time (h)
Length of Study(h)
% Recovery
% Penetrated
% Absorbed
s-s-flux (mcrg/cm2/h)
kp (cm/h)
n
Lag Time (h)
Ref.No
Propoxur
677
60% aq. Ethanol
Human
Abdomen
Full Thickness Skin
0.64
Static
4
24
9.67
1.7
0.000885
6
2.3
79
Propoxur
678
60% aq. Ethanol
Human
Abdomen
Isolated Epidermis
0.64
Static
4
24
39.2
25.87
4.9
0.0025521
6
1.1
79
Propoxur
679
60% aq. Ethanol
Rat
Dorsal
Full Thickness Skin
0.64
Static
4
24
7.27
1
0.00052
6
2.3
79
Propoxur
680
60% aq. Ethanol
Rat
Dorsal
Isolated Epidermis
0.64
Static
4
24
31.2
7.2
0.00375
6
1.2
79
Propoxur
681
60% aq. Ethanol
Pig
Ear
Full Thickness Skin
10
Perfused Pig Ear
4
4
5.33
2.5
0.000333
6
1
79
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IN VIVO DATA
Page 1 of 1
3
records found
Click the Study No. for further experimental detail
Chemical
Study No.
Vehicle
Species
Site
Dose (ml)
Area (cm2)
Concentration mg/ml
Exposure Time (h)
Length of Study (h)
% Absorbed
Maximal Flux (mcrg/cm2/h)
n
kp (cm/h)
Lag Time (h)
Reference Number
Propoxur
270
60% aq. Ethanol
Human
Volar Forearm
0.3
100
50
4
24
3.73
1
3
2E-05
2.4
79
Propoxur
271
60% aq. Ethanol
Rat
Back
0.1
10
15
4
72
15.1
8.7
4
0.00058
0
79
Propoxur
272
60% aq. Ethanol
Rat
Back
0.1
10
15
4
72
34.1
20.9
4
0.00139
0
79
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